Paula L Fischhaber
Professor
Faculty - Chemistry and Biochemistry
Brief Biography
After completing my undergraduate degree at C.U. Boulder, and my Ph.D. at the University of Washington in Seattle, I did postdoctoral research at the University of Texas Southwestern Medical Center at Dallas. Following my postdoc, I came to CSUN where I have been a faculty member in the Department of Chemistry and Biochemistry since 2005.
My research group is investigating the protein biochemistry of DNA repair in S. cerevisiae (baker’s yeast). In humans, failure to repair covalent modifications to DNA (DNA damage) via the DNA repair pathways results in genetic mutations that can lead to cancer. DNA damage is ubiquitous in living cells and much of it is unavoidable, so DNA repair pathways are crucial for survival.
My lab uses a variety of in vitro biochemical techniques as well as fluorescence microscopy to establish the temporal and spatial relationships among key proteins participating in DNA repair. Our ultimate goal is to understand how cells direct themselves toward the most appropriate DNA repair pathway to avoid burdensome levels of mutations.
Education
- Ph.D. 1998, University of Washington
- B.A. 1992, University of Colorado at Boulder
Research
Classes
| Class # | Catalog # | Title | Days | Time (Start-End) | Location | Syllabus |
|---|---|---|---|---|---|---|
|
||||||
|
|
||||||
Office Hours
| Day | Hours | Location | Description | |||
|---|---|---|---|---|---|---|
|
|
||||||
|
|
||||||